Skin Brightening
Human skin pigmentation is closely related to the metabolic activity of melanocytes. The melanin produced by melanocytes is transferred to keratinocytes through their dendritic process. Melanin synthesis occurs in the membrane-bound organelles called melanosomes in melanocytes, and its synthesis disorder can lead to abnormal skin pigmentation.
At present, cosmetics with whitening effects are attracting more and more attention. Biologically active substances with whitening effects have scientifically proven effects and have become a star in the skin care ingredient market. These products are not only aimed at brightening the overall skin tone but also aimed at hyperpigmentation caused by skin aging. With the popularity of such products in the market, skin whitening agent efficacy testing has become indispensable for the cosmetics and dermatological industries.
In order to meet market demand, cosmetic manufacturers continue to develop safer and more effective skin brightening products to deal with melasma and post-inflammatory hyperpigmentation. We have established an efficient analysis platform to provide scientific and reliable skin whitening/melanin production testing, provide valuablein vitro data for products, and help them reduce costs and increase the chances of formulation’s success before clinical trials.
Our Services
In order to better test the skin brightening effect of the product, we provide a variety of in vitro3D pigmented skin models for research, including reconstructed human pigmented epidermis, pigmented skin explants, and melanocyte cell lines (B16, etc.), these models all have a similar morphology as normal human skin, expressing keratinocyte differentiation and basement membrane markers. The parameters we detect include but are not limited to:
- Cell viability
- Quantitative analysis of melanin
- Evaluation of melanocyte proliferation and migration
- Pre-melanosome protein-PMEL17
- Tyrosinase activity and expression
- Macroscopic analysis
- Histological image analysis
Applications
- Evaluate the skin pigmentation and whitening efficacy of a single ingredient or finished product
- Any efficacy test related to skin whitening and pigmentation
- Customized testing according to customer needs
Creative BioMart is an advanced and professional cosmetic analysis company. We have established comprehensive technology platforms and our well-trained technicians can help customers design, develop, test, and analyze cosmetics, and provide customized one-stop solutions. Our high-quality service and service attitude have made us praised by customers from all over the world.
Welcome to contact us for project quotations and more detailed information.
For R&D and Further Manufacturing ONLY.
