Almost any product has the potential to cause dermal sensitization, or more specifically, allergic contact dermatitis (ACD). Like other allergic responses, allergic contact dermatitis is divided into two phases, induction and elicitation, and depends on the induction of an immune response. Although skin sensitization is not life-threatening, they can persist for a long time and decrease quality of life. It is therefore necessary to accurately identify and characterize all products that may cause skin sensitization. A product or substance is classified as a skin sensitizer when data show that it can produce a sensitization response "in a substantial number of persons" or has "positive results in an appropriate animal test". (UNECE, 2004, p. 152).
Animal models have previously been routinely used for skin sensitization testing, but there is now significant interest in new approaches that reduce the need for animal testing or replace animals altogether. The Non-animal approaches are highly potential and offer unparalleled opportunities for toxicologists, risk assessors and regulators to work collaboratively to achieve better outcomes that protect human health than in vivo approaches.
Skin sensitization testing requires a strong team and a wealth of expertise as support, it is not a one-step program. Creative BioMart has integrated toxicology, regulatory support and biochemistry teams and has extensive experience in skin sensitization testing, so choosing us as a partner ensures efficient project completion.
Our service is a flexible and customizable program that can be changed at any time during testing as needed. This kind of cooperation is based on the timely communication between the team and the customer, which can avoid unnecessary testing and save costs. In the service package, including biochemistry, toxicology, legal supervision, in silico and other content, to ensure that customers can complete the test at one time without changing partners. At present, Creative BioMart has provided high-quality services to many cosmetic developers and manufacturers around the world, and we are looking forward to cooperating with you.
Creative BioMart is a professional cosmetic analysis company, which aims to provide comprehensive analysis, development and manufacturing support services for the cosmetics industry. Our rich experience, numerous successful cases, and powerful data analysis systems make us confident to provide customers with excellent, high quality and precise services, and help customers meet regulatory requirements while deepening the understanding of raw materials and ensuring safer products.
Welcome to contact us for project quotations and more detailed information.